carnevalemanfredonia.it
» » Signaling Molecules As Targets in Cancer Therapy

eBook Signaling Molecules As Targets in Cancer Therapy download

by Vittorio De Franciscis,Laura Cerchia,Bertrand Tavitian

eBook Signaling Molecules As Targets in Cancer Therapy download ISBN: 1600212433
Author: Vittorio De Franciscis,Laura Cerchia,Bertrand Tavitian
Publisher: Nova Biomedical; 1 edition (July 2, 2006)
Language: English
Pages: 240
ePub: 1356 kb
Fb2: 1498 kb
Rating: 4.3
Other formats: lrf doc txt lit
Category: Medics
Subcategory: Medicine

Электронная книга "Signalling Molecules as Targets in Cancer Therapy", Vittorio de Franciscis, Laura Cerchia, Bertrand Tavitian

Электронная книга "Signalling Molecules as Targets in Cancer Therapy", Vittorio de Franciscis, Laura Cerchia, Bertrand Tavitian. Эту книгу можно прочитать в Google Play Книгах на компьютере, а также на устройствах Android и iOS. Выделяйте текст, добавляйте закладки и делайте заметки, скачав книгу "Signalling Molecules as Targets in Cancer Therapy" для чтения в офлайн-режиме.

This book presents state-of-the-art information on the molecules of cell signalling pathways that represent actual or future targets for cancer therapy

This book presents state-of-the-art information on the molecules of cell signalling pathways that represent actual or future targets for cancer therapy.

Vittorio De Franciscis’s books. Signaling Molecules as Targets in Cancer Therapy by. Vittorio De Franciscis, Vittorio De Franciscis.

Targeting large transmembrane molecules, including receptor tyrosine kinases, is a major pharmacological challenge. Laura Cerchia, Carla Lucia Esposito, Andreas H. Jacobs, Bertrand Tavitian, Vittorio de Franciscis. Specific oligonucleotide ligands (aptamers) can be generated for a variety o. More).

Authors and affiliations. Vittorio de Franciscis. Protocol The discovery of receptor tyrosine kinases: targets for cancer therapy. Paloma H. Giangrande. First Online: 31 January 2009. These molecules represent attractive targets for cancer diagnosis or therapy and therefore are subject to intensive investigation. Aptamers are small, highly structured nucleic acid molecules, isolated from combinatorial libraries by a procedure termed SELEX. Aptamers bind to a target molecule by providing a limited number of specific contact points imbedded in a larger, defined three-dimensional structure. The discovery of receptor tyrosine kinases: targets for cancer therapy.

These molecules represent attractive targets for cancer diagnosis or therapy and are therefore subject to intensive investigation. Aptamers are small nucleic acid molecules, isolated from combinatorial libraries by a procedure termed SELEX, that bind to a target molecule by providing a limited number of specific contact points embedded in a larger, defined three-dimensional structure. In some cases aptamers have the potential to inhibit the biological function of the molecule resulting in useful reagents for target validation in a variety of disease models. Download full-text PDF. Source.

Vittorio de Franciscis. Many signalling proteins involved in diverse functions such as cell growth and differentiation can act as oncogenes and cause cellular transformation. These molecules represent attractive targets for cancer diagnosis or therapy and are therefore subject to intensive investigation. Laura Cerchia, Jorg Hamm, Domenico Libri, Bertrand Tavitian, Vittorio de Franciscis

These molecules represent attractive targets for cancer diagnosis or therapy and are therefore subject to intensive investigation. Laura Cerchia, Jorg Hamm, Domenico Libri, Bertrand Tavitian, Vittorio de Franciscis. Istituto per l'Endocrinologia e l'Oncologia Sperimentale del CNR G. Salvatore, via Pansini 5, 80131 Napoli, Italy. Journal FEBS Letters.

Laura Cerchia, Amelia D'Alessio, Giovanni Amabile, Frederic Duconge, Carine Pestourie, Bertrand Tavitian, Domenico Libri and Vittorio de Franciscis

Laura Cerchia, Amelia D'Alessio, Giovanni Amabile, Frederic Duconge, Carine Pestourie, Bertrand Tavitian, Domenico Libri and Vittorio de Franciscis. Mol Cancer Res July 1 2006 4 (7) 481-488; DOI:10. Signaling and Regulation. Tyrosines in the MUC1 Cytoplasmic Tail Modulate Transcription via the Extracellular Signal-Regulated Kinase 1/2 and Nuclear Factor-κB Pathways. Eric J. Thompson, Kandavel Shanmugam, Christine L. Hattrup, Kari L. Kotlarczyk, Albert Gutierrez, Judy M. Bradley, Pinku Mukherjee and Sandra J. Gendler

Laura Cerchia, Carla Lucia Esposito, Andreas H. 4. Cerchia L, Hamm J, Libri D, Tavitian B, de Franciscis V (2002) Nucleic acid aptamers in cancer medicine.

Laura Cerchia, Carla Lucia Esposito, Andreas H. x. Published: November 24, 2009. FEBS Lett 528: 12–16. 5. Cerchia L, de Franciscis V (2007) Nucleic acid-based aptamers as promising therapeutics in neoplastic diseases. Methods Mol Biol 361: 187–200.

This book presents state-of-the-art information on the molecules of cell signalling pathways that represent actual or future targets for cancer therapy. By giving an update of the most promising approaches in this rapidly evolving field, the book contributes to the translation of the recent advances in the knowledge of intracellular signalling into the generation of innovative biomolecules as specific tools to target the most promising tumour-specific candidates. The book begins logically with the molecules first encountered along the signalling pathways, the membrane receptors for growth factors (Part I). Next, Part II presents several examples of intracellular molecular targets that are situated one step beyond in the pathways, while Part III addresses the difficult task of tuning the delicate balance between cell death and survival. In Part IV, the reader is taken into the practical problems raised by the therapy of specific cancers (glioma, childhood leukaemia), and into an original strategy from the field of nuclear medicine with the potential to generate innovative molecular-targeted cancer therapies.