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Select Format: Hardcover. ISBN13: 9780471255314.

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Novartis ACZ885 (canakinumab) – CANTOS study results. IL-1β inhibition as cancer therapy: Ilaris® + PDR001 in solid tumors. Inhibition of IL-1β with canakinumab will block the tumor-promoting effects of myeloid cells in the tumor microenvironment, so as to inhibit cancer cell growth and metastasis, and to promote protective immune response augmented by PD-1 inhibition with PDR001.

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