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eBook Follicular Dendritic Cells in Normal and Pathological Conditions (Molecular Biology Intelligence Unit) download

by Ernst Heinen

eBook Follicular Dendritic Cells in Normal and Pathological Conditions (Molecular Biology Intelligence Unit) download ISBN: 0412101416
Author: Ernst Heinen
Publisher: Chapman & Hall; 1 edition (December 1, 1995)
Language: English
Pages: 184
ePub: 1139 kb
Fb2: 1399 kb
Rating: 4.8
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Category: Different
Subcategory: Medicine and Health Sciences

Follicular dendritic cells (FDCs) are cells of the immune system found in primary and secondary lymph follicles of the B cell areas of the lymphoid tissue.

Follicular dendritic cells (FDCs) are cells of the immune system found in primary and secondary lymph follicles of the B cell areas of the lymphoid tissue. These cells were first described in 1965 and, although they have a very dendritic morphology, are not dendritic cells (DCs). Unlike DCs, FDCs are not derived from the bone-marrow hematopoietic stem cell, but are of mesenchymal origin.

Document type : Books : Book published as author, translator, et. Author, co-author : Heinen, Ernst.

Document type : Books : Book published as author, translator, etc. Discipline(s) : Life sciences : Anatomy (cytology, histology, embryology. Title : The follicular dendritic cells in normal and pathological conditions. Publication date : 1995. Publisher : Springer.

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious .

Follicular dendritic cell sarcoma (FDCS) is a rare neoplasm with a non-specific and insidious presentation further complicated by the difficult diagnostic and therapeutic assessment. It has a low to intermediate risk of recurrence and metastasis. To investigate whether recurrent genomic alterations may underlie the biology of follicular dendritic cell sarcoma and to identify potential contributory regions and genes, molecular inversion probe array analysis was performed on 14 independent formalin-fixed, paraffin-embedded samples. Abnormal genomic profiles were observed in 11 out of 14 (79%) cases.

Follicular dendritic cells (FDCs) are stromal cells residing in primary .

Follicular dendritic cells (FDCs) are stromal cells residing in primary follicles and in germinal centers of secondary and tertiary lymphoid organs (SLOs and TLOs). There, they play a crucial role in B-cell activation and affinity maturation of antibodies. Immune serum significantly improved antigen trapping, as did normal rat serum, but for the latter 25-times more volume was required. migrate into the follicle and transfer ICs to follicular (FO) B cells in a CR2-dependent manner (2). Subsequently, FO B cells transfer the ICs onto FDCs (3, 4). The Role of FDC-Bound ICs in B-Cell Responses.

Follicular dendritic cells (FDCs) that trap and retain antigens play a critical role both in the generation of this . In tonsils from the normal volunteers there are mainly secondary follicles with some hyperplasia, presumably a reflection of continuous antigenic stimulation (Fig.

Follicular dendritic cells (FDCs) that trap and retain antigens play a critical role both in the generation of this humoral immune response and in B cell memory by creating a three-dimensional network where B and T cells and antigen can interact (1, 2). Thus, it is not surprising that the humoral immune response deteriorates in HIV-1 infection, concomitant with the destruction.

Follicular dendritic cells normally reside in (and provide architectural support for) lymphoid follicles and present antigens to B lymphocytes. As such, follicular dendritic cell sarcomas typically arise at lymphoid tissue–rich anatomic sites. 30-34 Among dendritic cell tumors, follicular dendritic cell sarcoma is most likely to be confused with other soft tissue tumors. Follicular dendritic cell sarcoma affects adults over a wide age range, with a peak in young to middle-aged adults, with no gender predilection

Molecular biology intelligence unit. Download DOC book format

Molecular biology intelligence unit. Genre/Form: Aufsatzsammlung gnd. Personal Name: Heinen, Ernst 1947- Sonstige (DE-588)134071476. Download DOC book format.

In: Heinen E (ed) Follicular dendritic cells in normal and pathological conditions. J Cell Pathol 1: 3–10Google Scholar. Springer, Berlin Heidelberg New York Tokyo, pp 53–78Google Scholar.

Molecular Biology Intelligence Unit.

Published February 1996 by Springer. Molecular Biology Intelligence Unit.