eBook Bioreversible Carriers in Drug Design: Theory and Application download
by Edward B. Roche
Author: Edward B. Roche
Publisher: Pergamon Pr (June 1, 1987)
ePub: 1604 kb
Fb2: 1839 kb
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Subcategory: Medicine and Health Sciences
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Bundgaard H. Design of bioreversible drug derivatives and the utility of the double prodrug concept. In: Roche EB, ed. Bioreversible Carriers in Drug Design: Theory and Application. eBook Packages Springer Book Archive. Reprints and Permissions. New York: Pergamon Press; 1987:13–94. New York: Pergamon Press; 1987:164–195. 16. Higuchi WI, Yu C-D. Prodrugs in transdermal delivery. In: Kydonieus AF, Berner B, eds. Transdermal Delivery of Drugs. Personalised recommendations.
August 12, 2010 History. Theory and Application. Published June 1987 by Pergamon Pr. Written in English. Bioreversible Carriers in Drug Design Close. 1 2 3 4 5. Want to Read. Are you sure you want to remove Bioreversible Carriers in Drug Design from your list? Bioreversible Carriers in Drug Design.
Personal Name: Roche, Edward . C) 2017-2018 All rights are reserved by their owners.
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Prodrugs are bioreversible derivatives of drug molecules that undergo an enzymatic and/or chemical transformation in vivo to release the active parent drug, which can then exert the desired pharmacological effect. In both drug discovery and development, prodrugs have become an established tool for improving physicochemical, biopharmaceutical or pharmacokinetic properties of pharmacologically active agents. About 5-7% of drugs approved worldwide can be classified as prodrugs, and the implementation of a prodrug approach in the early stages of drug discovery is a growing trend.
Drug design, often referred to as rational drug design or simply rational design, is the inventive process of finding new medications based on the knowledge of a biological target. The drug is most commonly an organic small molecule that activates or inhibits the function of a biomolecule such as a protein, which in turn results in a therapeutic benefit to the patient.
Find Edward Roche's contact information, age, background check, white pages, pictures, bankruptcies, property records . Bioreversible Carriers In Drug Design: Theory And Application - ISBNdb (books and publications). author: Edward B. Roche.
Find Edward Roche's contact information, age, background check, white pages, pictures, bankruptcies, property records, liens & civil records. Corporate Networks, International Telecommunications And Interdependence: Perspectives From Geography And Information Systems - ISBNdb (books and publications). author: Edward M. Design Of Biopharmaceutical Properties Through Prodrugs And Analogs - ISBNdb (books and publications).
Presents several applications of computational methods to real world problems in the drug design field. Helps to avoid a "black-box" approach to in silico drug discovery. Constitutes an actual textbook for students in the area of molecular modeling and drug discovery
Presents several applications of computational methods to real world problems in the drug design field. Constitutes an actual textbook for students in the area of molecular modeling and drug discovery. Gives the reader the adequate background to face the current challenges of the field. In Silico Drug Discovery and Design: Theory, Methods, Challenges, and Applications describes the theoretical framework, methods, practical applications and case examples relevant to computer-aided drug lead discovery and design.
A drug carrier is any substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness .
A drug carrier is any substrate used in the process of drug delivery which serves to improve the selectivity, effectiveness, and/or safety of drug administration. Drug carriers are primarily used to control the release of a drug into systemic circulation. Drug carriers are also used to improve the pharmacokinetic properties, specifically the bioavailability, of many drugs with poor water solubility and/or membrane permeability. A wide variety of drug carrier systems have been developed and studied, each of which has unique advantages and disadvantages.